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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RAB4A All Species: 31.82
Human Site: Y189 Identified Species: 50
UniProt: P20338 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P20338 NP_004569.2 213 23871 Y189 R M G S G I Q Y G D A A L R Q
Chimpanzee Pan troglodytes XP_001145983 561 60056 D415 K R G G R L R D G Q L V S Q R
Rhesus Macaque Macaca mulatta XP_001092499 200 21803 S180 G I Q Y G D A S L R Q L R Q P
Dog Lupus familis XP_536353 218 24344 Y194 R M G S G I Q Y G D A A L R Q
Cat Felis silvestris
Mouse Mus musculus P56371 213 23920 Y189 R M G S G I Q Y G D A A L R Q
Rat Rattus norvegicus P05714 213 23888 Y189 R M G S G I Q Y G D A A L R Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90965 212 23503 I187 N E A N G I K I G P Q H A A T
Frog Xenopus laevis NP_001080671 213 23840 Y189 R M W S G I Q Y G D A S P R H
Zebra Danio Brachydanio rerio Q6PHI9 213 23984 Y189 R M G S G I Q Y G D A A L R Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_523777 213 23555 Y189 R I G S G I Q Y G G A A L R N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791693 210 23410 Y189 R M G S G I Q Y G D S T L R K
Poplar Tree Populus trichocarpa
Maize Zea mays P49103 209 22983 V187 N E S Y G I K V G Y V V P G Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P28188 203 22630 P184 P A G N N A R P P T V Q I R G
Baker's Yeast Sacchar. cerevisiae P38555 223 24451 A194 D S S A N G N A N G A S A P N
Red Bread Mold Neurospora crassa P33723 203 22458 S185 A T N N T K A S V N V S P G H
Conservation
Percent
Protein Identity: 100 31.1 76.5 97.2 N.A. 97.6 98.5 N.A. N.A. 52.5 85.4 96.2 N.A. 76.5 N.A. N.A. 85.4
Protein Similarity: 100 34.4 82.1 97.7 N.A. 99.5 99.5 N.A. N.A. 69 90.6 98.1 N.A. 87.7 N.A. N.A. 91
P-Site Identity: 100 13.3 6.6 100 N.A. 100 100 N.A. N.A. 20 73.3 100 N.A. 80 N.A. N.A. 80
P-Site Similarity: 100 46.6 20 100 N.A. 100 100 N.A. N.A. 33.3 80 100 N.A. 86.6 N.A. N.A. 93.3
Percent
Protein Identity: N.A. 51.6 N.A. 40.8 43 39.4
Protein Similarity: N.A. 67.6 N.A. 59.1 60.5 58.2
P-Site Identity: N.A. 26.6 N.A. 13.3 6.6 0
P-Site Similarity: N.A. 33.3 N.A. 33.3 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 7 0 7 14 7 0 0 54 40 14 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 0 0 7 0 7 0 47 0 0 0 0 0 % D
% Glu: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 60 7 74 7 0 0 74 14 0 0 0 14 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 14 % H
% Ile: 0 14 0 0 0 67 0 7 0 0 0 0 7 0 0 % I
% Lys: 7 0 0 0 0 7 14 0 0 0 0 0 0 0 7 % K
% Leu: 0 0 0 0 0 7 0 0 7 0 7 7 47 0 0 % L
% Met: 0 47 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 14 0 7 20 14 0 7 0 7 7 0 0 0 0 14 % N
% Pro: 7 0 0 0 0 0 0 7 7 7 0 0 20 7 7 % P
% Gln: 0 0 7 0 0 0 54 0 0 7 14 7 0 14 40 % Q
% Arg: 54 7 0 0 7 0 14 0 0 7 0 0 7 60 7 % R
% Ser: 0 7 14 54 0 0 0 14 0 0 7 20 7 0 0 % S
% Thr: 0 7 0 0 7 0 0 0 0 7 0 7 0 0 7 % T
% Val: 0 0 0 0 0 0 0 7 7 0 20 14 0 0 0 % V
% Trp: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 14 0 0 0 54 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _